1.Date of the board of directors resolution or date of occurrence of the change:2024/04/24 2.Position (Please enter chairperson or president/general manager):Chairman 3.Name of the previous position holder:Ching-Hua Gu 4.Resume of the previous position holder:Chairman of TOP Biological Technology Company Limited 5.Name of the new position holder:Sze-Yuan Yang 6.Resume of the new position holder:General Manager of TSH Biopharm Corporation Limited 7.Circumstances of change (Please enter ”resignation”, ”dismissal”, ”term expired” , ”job relocation”, ”severance”, ”retirement”, ”death” or ”new appointment”):New appointment 8.Reason for the change:Re-election of directors and supervisors. New directors recommended Sze-Yuan Yang as Chairman. 9.Effective date of the new appointment:2024/04/24 10.Any other matters that need to be specified(the information disclosure also meets the requirements of Article 7, subparagraph 6 of the Securities and Exchange Act Enforcement Rules, which bring forth a significant impact on shareholders rights or the price of the securities on public companies.):None