1.Date of occurrence of the event:2025/12/02

2.Company name:CHUANG YI BIOTECH CO., LTD.

3.Relationship to the Company (please enter ”head office” or ”subsidiaries”):subsidiaries

4.Reciprocal shareholding ratios:None

5.Cause of occurrence:The Company’s stock affairs were originally handled by the Stock Transfer Agency Department of Yuanta Securities Co., Ltd.
Starting from January 1,2026, they will be handled by the Stock Transfer Agency Department of Capital Securities Corp.

6.Countermeasures:None.

7.Any other matters that need to be specified(the information disclosure also meets the requirements of Article 7, subparagraph 9 of the Securities and Exchange Act Enforcement Rules, which brings forth a significant impact on shareholders rights or the price of the securities on public companies.):
Starting from January 1,2026, shareholders of CHUANG YI BIOTECH CO., LTD may handle matters such as stock transfer, dividend or share collection, address change, stock loss reporting, pledge establishment or release, seal specimen change or loss reporting, and other stock-related services by visiting or mailing the required documents to the Stock Transfer Agency Department of Capital Securities Corp.
The address and contact information are listed below.
Address: B2, No. 97, Section 2, Dunhua South Road, Da’an District, Taipei City.
Tel: (02) 2703-5000.