H&E stained sections representing the tissue block submitted to CellMax life laboratory has been reviewed by the pathologist for tumor content evaluation and macro dissection. Next-Generation sequencing is performed on DNA isolated form a formalin—fixed paraffin-embedded tissue sections using the Illumina MiSeq platform.

CellMax TBs is a tissue biopsy NGS test with a custom gene panel that provides coverage of NCCN guideline recommended sites for solid tumors. The test detects mutations across 74 genes, including oncogenes, tumor suppressor genes, and tumor stimulator genes. The test id capable of detecting somatic mutations including single nucleotide variants (SNVs), small insertions and deletions (InDels), copy number variations (CNV), gene fusions, and microsatellite instability (MSI).