AlphaSolid® is a tissue biopsy test designed for patients with advanced solid cancers. Our patented UniqSeqⓇ technology detects tumor DNA for comprehensive genomic analysis.
AlphaSolid® detects the four classes of variations (SNV, INDEL, fusion, and CNV) and the two genomic signatures of immunotherapy (MSI and TMB) in 118 NCCN-recommended genes associated with major cancer types. With this data, IMB Dx can provide information on appropriate therapy options and related on-going clinical trials.
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Analysis Report
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| SNVs & InDels(117) | CNVs(27) | Fusions(10) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| ABL1 | AKT1 | AKT2 | ALK | APC | AR | ARAF | AKT1 | FGFR2 | ALK |
| ARID1A | ATM | BARD1 | BRAF | BRCA1 | BRCA2 | BRIP1 | AR | FGFR3 | BCR |
| BTK | CBL | CCND1 | CCND2 | CCNE1 | CD274 | CDH1 | BRAF | KDR | BRAF |
| CDK12 | CDK4 | CDK6 | CDKN2A | CEBPA | CHEK1 | CHEK2 | BRCA1 | KIT | EGFR |
| CSF1R | CTNNB1 | DDR2 | DPYD | EGFR | ERBB2 | ERBB3 | CCND1 | KRAS | FGFR2 |
| ESR1 | FANCL | FBXW7 | FGFR1 | FGFR2 | FGFR3 | FLT3 | CCND2 | MAPK1 | FGFR3 |
| GATA3 | GNA11 | GNAQ | GNAS | HRAS | IDH1 | IDH2 | CCNE1 | MDM2 | NTKR1 |
| IGF1R | JAK2 | JAK3 | KDM6A | KDR | KEAP1 | KIT | CD274 | MET | NTRK2 |
| KRAS | MAP2K1 | MAP2K2 | MAPK1 | MAPK3 | MDM2 | MET | CDK12 | MYC | RET |
| MLH1 | MPL | MSH2 | MSH6 | MTOR | MYC | MYCN | CDK4 | MYCN | ROS1 |
| NF1 | NF2 | NFE2L2 | NOTCH1 | NPM1 | NRAS | NTRK1 | CDK6 | PDGFRA | |
| NTRK2 | NTRK3 | PALB2 | PDCDILG2 | PDGFRA | PDGFRB | PIK3CA | EGFR | PIK3CA | |
| PIK3R1 | PMS2 | PPP2R1A | PPP2R2A | PTEN | PTPN11 | RAD51B | ERBB2 | RAF1 | |
| RAD51C | RAD51D | RAD54L | RAF1 | RB1 | RET | RHEB | FGFR1 | ||
| RHOA | RIT1 | RNF432 | ROS1 | RUNX1 | SETD2 | SMAD4 | |||
| SMO | STAG2 | STK11 | TCF7L2 | TERT | TOP2A | TP53 | |||
| TSC1 | TSC2 | U2AF1 | VHL | UGT1A1 | |||||
